From the FDR Drive – South to Brooklyn Bridge exit. Once on the Bridge, stay in the right lane and take the first exit off the Bridge, which is Cadman Plaza West. After a short distance on the exit ramp, you will reach a fork in the roadway. Take the right fork at the end of the ramp, enter roadway and then bear left. Stay in the right lane of the three lane road and come all the way downhill to Water Street. Make a right turn on Water Street, and the entrance is on your left.
From the George Washington Bridge – Take the FDR drive south and see the above directions.
From the Lincoln Tunnel – To West Side Highway South. Take the West Side Highway around the tip of Manhattan and back Northbound on the FDR. Drive to the Brooklyn Bridge exit and follow the above directions.
From the Holland Tunnel – Take Canal Street exit to Varick Street. Make a right turn on to Varick Street and follow to Chambers Street. Make a left onto Chambers Street and follow signs to the entrance of Brooklyn Bridge. Follow the above directions from the Brooklyn Bridge.
From the Brooklyn Queens Expressway/ Long Island Expressway – Take the LIE  West to the BQE  towards Manhattan and get off at exit 28, Cadman Plaza West. At the end of the exit ramp, make a right and come down two blocks to Water Street. Make a right and the entrance is on your left.
From the Manhattan Bridge – Make a right on Tillary Street [second light]. Go five blocks to Cadman Plaza West and make a right turn. Follow road as it bears left slightly and go downhill in the right lane to Water Street. Make a right on Water Street and entrance will be on your left.
From the Battery Tunnel – Take the first exit, Hamilton Avenue. Make first left, which is the Brooklyn Queens Expressway Eastbound. Take this to the Cadman Plaza exit. At the bottom of the ramp, make a right turn and proceed to the traffic light. Make a legal U turn at the light and stay in the right lane. Follow the road straight down to Water Street. Make a right at Water Street and the entrance will be on your left.
From the Verazzano Bridge – Follow the signs for 278-Battery Tunnel [center lane] as you get off the Verazzano Bridge. Follow the signs for the BQE and take the BQE to Cadman Plaza West. Get off at Cadman Plaza West and make a right at the bottom of the ramp. Stay in the left lane and make a legal U turn at the traffic light. Then, stay in the right lane and come all the way down the hill to Water Street. Make a right turn on to Water Street and entrance will be on your left.